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Optical spectroscopy to diagnose Alzheimer's disease in vivo

Eugene B. Hanlon, Donald F. Siwek, Ann C. Mckee, Neil W. Kowall, Hui Fang, Edward I. Vitkin, and Lev T. Perelman

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Abstract

Neurodegenerative pathologies such as Alzheimer's disease present protein aggregates that scatter light. We are developing techniques to detect their characteristic spectra in vivo as a basis for definitive, non-invasive diagnosis and for monitoring experimental therapeutics.

© 2004 Optical Society of America

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