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Proposed advantages of using mid-IR wavelengths for morphological characterization of pre-cancerous tissue using elastic-scattering spectroscopy

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Abstract

It is proposed that elastic-scattering spectroscopy with mid-IR wavelengths may provide increased sensitivity to nuclear sizes in dysplastic tissue and reduce the scattering effects of smaller organelles. Diffuse light due to multiple-scattering can also be minimized due to the intrinsically high water absorption. This could potentially become a useful tool for characterizing dysplastic tissue.

© 2004 Optical Society of America

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