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Tumor oxygenation measured by non-invasive broadband diffuse reflectance spectroscopy predicts photodynamic therapy outcome

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Abstract

Photodynamic therapy (PDT) requires oxygen to damage tumor. We demonstrated that the fractional change in tumor oxygenation, measured by diffuse reflectance spectroscopy, shortly after versus before PDT significantly correlates with time-to-regrowth of the same tumor.

© 2004 Optical Society of America

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