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Conferences > BIO > 2004 > SA > SA5

Contrast agent enhanced fluorescence imaging for early detection of arthritis

B. Ebert, R. Macdonald, D. Petzelt, H. Rinneberg, T. Fischer, I. Wojner, D. von Stieglitz, M. Taupitz, B. Hamm, K. Licha, M. Schirner, and V. Krenn

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Abstract

Fluorescence imaging in the near-infrared (NIR) spectral range following intravenous administration of optical contrast agents (dyes) has been investigated as a new tool for the detection of inflammatory joint diseases in an animal model in vivo. Our study reveals that NIR dyes of the cyanine class accumulate in inflammatory joints and could be used to detect early stages of joint inflammation.

© 2004 Optical Society of America

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