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The Spectral Dependence of Fiberoptic Probe Pressure on Tissue During In Vivo Diffuse Reflectance Spectroscopy

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Abstract

The effect of fiberoptic probe pressure on tissue on the measured diffuse reflectance spectra has been evaluated, using normal skin in vivo as a model tissue, with both fiber-to-fiber probe geometry (standard contact probe) and imaging geometry (wide field illumination and fiber collection) for the wavelength ranges 400-415, 415-440, 440-480, 480-520, 520-560, 560-600 and 600-640 nm. The implications for endoscopic point spectroscopy are discussed.

© 2004 Optical Society of America

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