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Cerebral Hemodynamics during Cortical Spreading Depression at different states of brain oxygenation and ventilation

T. Durduran, G. Yu, J. P. Culver, C. Cheung, D. Furuya, J. H. Greenberg, and A. G. Yodh

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Abstract

We measure cerebral blood flow, blood oxygen saturation and volume during KCl induced cortical spreading depression in rat brain. Changes in peak duration, peak-to-peak delay and spreading speed during normoxia, hypoxia, hypercapnia and hypocapnia are quantified.

© 2002 Optical Society of America

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