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Comparing CBV and Hb saturation changes in rat somatosensory cortex measured with fMRI and DOT

A. M. Siegel, J. P. Culver, J. J. A. Marota, J. B. Mandeville, and D. A. Boas

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Abstract

The time courses of both CBV and oxygenation following electrical forepaw stimulation were measured using Diffuse Optical Tomography (DOT). Results matched those obtained with fMRI. Thus, DOT can accurately measure the temporal and spatial evolution of cerebral hemodynamic events.

© 2002 Optical Society of America

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