Induction of apoptosis and necrosis following pulsed laser irradiation of intracellular pigment microparticles

Dariusz Leszczynski; Costas M. Pitsillides; R. Rox Anderson; Charles P. Lin

doi:10.1364/BIO.1999.CWC5

Biomedical Optics
OSA Technical Digest (Optica Publishing Group, 1999),
paper CWC5
•https://doi.org/10.1364/BIO.1999.CWC5

Induction of apoptosis and necrosis following pulsed laser irradiation of intracellular pigment microparticles

Dariusz Leszczynski, Costas M. Pitsillides, R. Rox Anderson, and Charles P. Lin

Biomedical Topical Meeting 1999

Munich Germany
ISBN: 1-55752-584-6

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Laser Microeffects (CWC)

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D. Leszczynski, C. M. Pitsillides, R. R. Anderson, and C. P. Lin, "Induction of apoptosis and necrosis following pulsed laser irradiation of intracellular pigment microparticles," in Biomedical Optics, OSA Technical Digest (Optica Publishing Group, 1999), paper CWC5.

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Abstract

Absorbing microparticles can be used for targeted cell killing when irradiated by short laser pulses. The physical mechanism of cell killing is the generation of transient microcavitation bubbles around the heated particles.

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