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Non-invasive determination of concentration of compounds in strongly absorbing biological tissue

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Abstract

We describe a non-invasive method for the determination of optical parameters of biological tissue. An advantage of this method is that it does not rely on diffusion theory, thus it is applicable to strongly absorbing media and at small source-detector separations. The method was applied to the determination of haemoglobin in biological tissue.

© 1999 Optical Society of America

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