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Monitoring blood flow during vascular-targeted photodynamic therapy using laser speckle imaging

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Abstract

Laser speckle imaging was used to monitor blood flow dynamics during and after vascular-targeted photodynamic therapy (V-PDT). The results show that blood flow and blood perfusion rate was decreased after V-PDT, while the blood flow in veins could be partially increased after treatment. This study suggest that the LSI system hold the potential for quantitative assessment of vascular damage for V-PDT.

© 2016 Optical Society of America

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